PRP INJECTIONS IN ORTHOPEDICS

 

What is PRP?

PRP (platelet-rich plasma) is autologous blood that contains platelets higher than normal.

Normal platelet count is 4.5 × 105/μL, but PRP has 4-5 times the normal value.

How does PRP work?

Platelets secrete growth factors like platelet-derived growth factor (PDGF), transforming growth factor beta (TGF-β), vascular endothelial growth factor (VEGF), and epithelial growth factor (EGF), which improve the healing process.

Platelets also have adhesion molecules like fibrin, fibronectin, and vitronectin, which promote bone formation.

How is PRP prepared?

The patient’s own blood drawn is then centrifuged in a machine to separate platelets. This centrifugation allows the separation and collection of the buffy coat layer that contains PRP. This prepared PRP is then administered to the site of injury or into the joints.


Do we need to be admitted to the hospital for the the PRP procedure?

It’s a daycare procedure done in the outpatient department; you will be sent home immediately after the procedure.

How long do we need to take rest after the procedure?

Technically, there is no need for rest, but it’s advisable for 24–48 hours of less activity to be on the safer side.

How painful is the PRP injection?

It’s not a painful procedure on a scale of 10; it’s just 1.


What are it’s side effects? 

As PRP is prepared from your blood, it doesn’t have any side effects. It's a 100% safer procedure.


How long does it take PRP to act ?

Usually it takes around 3-4 weeks .

How long does PRP work ?

It depends on the magnitude of the problem , at what stage the PRP is administered and also varies from person to person.

How many PRP injections are needed?

It depends on chronicity and the magnitude of the problem; it varies from 1–3 injections given at 3–4-week intervals.

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